Acqua di S.M.Novella is Officina Profumo Farmaceutica di Santa Maria Novella’s oldest fragrance. It is the perfume that Caterina de’ Medici commissioned the Dominican monks to create in 1533, and she took it with her to France when she married Enrico di Valois. For this reason this fragrance is identified as a perfume rather than with a cologne. It is a bouquet of fresh citrus notes with a base of Calabrian bergamot.

The mold for the bottle is reminiscent of the glass bottles Officina has used over the last two centuries of its history, and it is used for all the other Santa Maria Novella colognes which have been created subsequently.